TL;DR: The usage of brown alga (Bifurcaria bifurcata) within the biosynthesis of copper oxide nanoparticles of dimensions five–forty five nm is documented for the first time and these nanoparticles ended up observed to show higher antibacterial exercise in opposition to two distinctive strains of microbes. The website is protected. The https://www.directivepublications.org/journal-of-applied-nanoscience/