It can be done that the TCAB1-mediated “switch” is not captured through the conformation characterized during the cryo-EM structure. Characterizing a larger fraction of the holoenzyme particles within the active chromatographic fraction will likely cause the identification of additional conformational states. The cryo-EM characterization of human telomerase also reveals the https://mariooibwn.blogginaway.com/28890229/top-guidelines-of-endolift-lazer-pozu