Butabarbital will minimize the extent or influence of amlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. butabarbital will reduce the extent or effect of sufentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar. butabarbital will reduce the extent or result of ramelteon by affecting hepatic/intestin... https://wille776rzg3.signalwiki.com/user