Pentobarbital will decrease the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of abiraterone by affecting hepatic/intestinal enz... https://bookmarkleader.com/story20332918/tutto-ci%C3%B2-che-riguarda-what-is-nembutal-pentobarbital